NFL Week 10 QB Start 'Em, Sit 'Em: New Quarterbacks, New Teams, DFS Value, Props and Parlays

| Friday, November 13, 2026 | Week 10 Sunday and Monday

Week 10 matchups | NFL picks | NFL injury report | NFL depth charts | NFL projections | NFL props | AI NFL parlay builder

This is not an ordinary week at quarterback. There are new faces in new places, veterans trying to save their seasons, rookies getting their first starts, and injuries that could swing both fantasy lineups and betting boards.

If you're setting lineups, building DFS rosters or betting quarterback props, pay attention to the depth charts this week. Here are the quarterbacks to start, the ones to avoid, the best matchups and where the betting value could be hiding.

The Biggest Quarterback Storylines

1. Kirk Cousins, Vikings at Packers

New team: Las Vegas to Minnesota.

Cousins is the biggest veteran storyline of the weekend. Minnesota traded for him at the deadline, and he could step into the starting job with Kyler Murray listed as doubtful with a hamstring injury and Carson Wentz listed as questionable. Wentz turned the ball over three times in last week's loss to Buffalo.

Fantasy outlook: Wait for the starting announcement. Cousins brings experience and could be steady, but learning a new offense midseason adds risk. He does get Justin Jefferson, Jordan Addison and T.J. Hockenson.

Props: If he starts, his passing yards, passing touchdowns and interceptions are all worth researching once the lines post.

DFS: Not a cash-game core until he's confirmed. He could be an interesting low-owned tournament play. Vikings at Packers matchup

2. Carson Beck, Cardinals vs. Rams

First NFL start.

Beck makes his first start against the Rams after Gardner Minshew went on injured reserve with an elbow injury that's expected to end his season. It's a big opportunity for the rookie and a tough introduction. Arizona is a 9.5-point home underdog and has Michael Wilson on injured reserve.

Fantasy outlook: SIT in one-quarterback leagues.

Props: Passing yards, passing touchdowns and interceptions are the markets to watch for a rookie in a tough spot.

DFS: A contrarian tournament play, not a cash-game option. His legs and low ownership give him some upside, but the floor is dangerous. Rams at Cardinals matchup

3. Deshaun Watson, Browns vs. Texans

Back in the lineup, against his old team.

Watson is expected to return against the Texans after missing last week's game while in concussion protocol. Shedeur Sanders started in his place and threw for 297 yards and two touchdowns on 19-of-31 passing in a 23-22 overtime loss to New Orleans.

Fantasy outlook: Low-end QB2. Houston is a 4.5-point road favorite with a 40.5 total, so this projects as a low-scoring game.

Props: Passing yards and passing touchdowns lean low in this environment. Check whether a rushing number posts.

DFS: A salary-dependent tournament play, with safer options on the board. Texans at Browns matchup

4. Drew Lock, Seahawks at Raiders

Filling in for Sam Darnold.

Darnold is out until late November, which puts Lock in line to start. The catch: Lock is listed as questionable himself. Seattle is a 6.5-point favorite, so the game script could lean on the run.

Fantasy outlook: A Superflex emergency option, not a QB1.

Props: Passing yards and interceptions are the ones to research.

DFS: Cheap tournament play only. Seattle being favored doesn't mean a big passing day. Seahawks at Raiders matchup

5. Jacoby Brissett, Ravens vs. Chargers (Monday)

New team: Arizona to Baltimore.

With Lamar Jackson on injured reserve until mid-December, Brissett arrives off 1,719 yards and 10 touchdowns in eight Arizona starts. Baltimore is a 4.5-point favorite, and the 38.5 total is the lowest of the week.

Fantasy outlook: Superflex consideration once he's confirmed as the starter. Not a must-start in one-quarterback leagues.

Props: Passing yards and touchdowns, with a low total and a new offense working against him.

DFS: A salary-saving tournament play only, and only after his status is confirmed. Monday night also matters for late swaps. Chargers at Ravens matchup

6. Fernando Mendoza, Raiders vs. Seahawks

Rookie's first career start.

With Cousins gone to Minnesota, the Raiders named Mendoza their starter, with Aidan O'Connell behind him. Seattle's defense is a tough first assignment.

Fantasy outlook: Deep Superflex consideration only.

Props: Passing yards, touchdowns and interceptions for a rookie in his debut.

DFS: Not a priority play.

QB Start 'Em: Top Fantasy Options

Tier 1: Must Start

Josh Allen, Bills at Jets. Elite dual-threat production against a Jets team that's 2-7. Buffalo is an 8.5-point favorite with a 50.5 total. Props to research: passing yards, rushing yards and anytime touchdown. Bills at Jets matchup

Patrick Mahomes, Chiefs at Falcons. High-end passing upside with Rashee Rice, Xavier Worthy and deadline pickup Josh Downs to throw to. Kansas City is a 3-point favorite with a 47.5 total. Props to research: passing yards and passing touchdowns. Chiefs at Falcons matchup

Joe Burrow, Bengals vs. Steelers. A high-upside quarterback in a 49.5-total division game, with Ja'Marr Chase and Tee Higgins. Props to research: passing yards and passing touchdowns. Steelers at Bengals matchup

Brock Purdy, 49ers at Cowboys. The best quarterback environment on the board: a 55.5 total, the week's highest. Excellent tournament upside, even with Brandon Aiyuk out, since deadline pickup Keenan Allen joins the room. Props to research: passing yards and passing touchdowns. 49ers at Cowboys matchup

Tier 2: Strong Starts

Drake Maye, Patriots at Lions. A strong matchup in one of the week's best early games, with a 49.5 total. Passing and rushing upside. Props to research: passing yards and rushing yards. Patriots at Lions matchup

Jared Goff, Lions vs. Patriots. A strong offensive environment at home. Amon-Ra St. Brown is his most dependable target but is listed as questionable, so watch that report. Props to research: passing yards and passing touchdowns.

Trevor Lawrence, Jaguars at Titans. Jacksonville is a 10.5-point favorite over the 1-7 Titans. An efficient game script with rushing and touchdown upside. Props to research: passing touchdowns and rushing yards once posted. Jaguars at Titans matchup

Matthew Stafford, Rams at Cardinals. Arizona sets up well for a productive afternoon. Puka Nacua is on injured reserve, which reshapes the target tree. Props to research: passing yards and passing touchdowns.

Tier 3: Matchup-Dependent

• Bryce Young, Panthers at Saints: Superflex consideration in a 48.5-total game. Panthers at Saints matchup


• Michael Penix Jr., Falcons vs. Chiefs: Tournament upside in a tough matchup.


• Dak Prescott, Cowboys vs. 49ers: A great game environment, but George Pickens is listed as questionable.


• Aaron Rodgers, Steelers at Bengals: A solid veteran in a competitive division game.


• Geno Smith, Jets vs. Bills: Deep-league only against Buffalo.


• Tyler Shough, Saints vs. Panthers: A Superflex option.


• C.J. Stroud, Texans at Browns: A matchup-dependent QB2 in a low-total game.


• Cam Ward, Titans vs. Jaguars: A tough matchup against a heavy favorite.

QB Sit 'Em: Quarterbacks to Avoid

In standard one-quarterback leagues, steer clear of:

1. Carson Beck: First start against the Rams. Too much uncertainty.


2. Drew Lock: Questionable himself, and not a high-volume spot.


3. Fernando Mendoza: A rookie debut against Seattle.


4. Deshaun Watson: First game back in a 40.5-total game.


5. Jacoby Brissett: New team, new offense and the week's lowest total.


6. Kirk Cousins: A possible debut with little time to prepare.


7. Geno Smith: Buffalo is a tough defensive matchup.


8. Cam Ward: Jacksonville's defense and game script create concerns.

None of these are automatic benches in Superflex, where quarterback scarcity changes the math.

Quarterback Prop Leans

Week 10 quarterback props haven't posted on our NFL props page yet, so these are directions to research, not numbers. Compare each posted line against our NFL projections before you bet.

• Josh Allen: passing yards OVER, rushing yards OVER


• Patrick Mahomes: passing yards OVER, passing touchdowns OVER


• Joe Burrow: passing yards OVER


• Brock Purdy: passing yards OVER


• Drake Maye: rushing yards OVER


• Jared Goff: passing yards OVER


• Carson Beck: passing yards UNDER


• Drew Lock: passing yards UNDER


• Fernando Mendoza: passing yards UNDER


• Deshaun Watson: passing yards UNDER

Recheck availability and starting announcements before using any of them.

QB Parlay Ideas

Parlay 1: The Veteran Passer

• Josh Allen over passing yards


• Patrick Mahomes over passing touchdowns


• Joe Burrow over passing touchdowns

Parlay 2: The Dual-Threat Special

• Josh Allen over rushing yards


• Drake Maye over rushing yards


• Trevor Lawrence over passing touchdowns

Parlay 3: The New-Quarterback Fade

• Carson Beck under passing yards


• Drew Lock under passing yards


• Fernando Mendoza under passing yards

Parlay 4: The Shootout in Dallas

• Brock Purdy over passing yards


• Dak Prescott over passing touchdowns


• Christian McCaffrey over receptions

These are construction ideas with correlated legs, not guaranteed value. Our side on the 49ers-Cowboys total is on the game page. Let the AI NFL parlay builder price a ticket from the real board, or move a spread with the NFL teaser generator.

DFS Quarterback Value

Cash-game targets: Josh Allen, Patrick Mahomes, Drake Maye and Joe Burrow.

Tournament targets: Brock Purdy, Dak Prescott, Matthew Stafford and Michael Penix Jr.

Low-ownership speculative plays: Carson Beck, Drew Lock and Kirk Cousins if he's confirmed as Minnesota's starter.

Stacking: 49ers-Cowboys has the highest total on the board at 55.5, so start your quarterback stacks there. Some combinations:

• Purdy plus Christian McCaffrey or Mike Evans (if he's cleared)


• Prescott plus CeeDee Lamb


• Mahomes plus Rashee Rice


• Maye plus a Patriots receiver


• Goff plus Amon-Ra St. Brown (if he's cleared)

Check prices, inactives and projected ownership before you lock. Our NFL DFS tools line up price against production for every quarterback.

Weekend NFL Betting Board

From our board as of Friday morning. Lines move, so check the Week 10 matchups page before you bet.

• Patriots at Lions: DET -2.5, total 49.5


• Chiefs at Falcons: KC -3, total 47.5


• Texans at Browns: HOU -4.5, total 40.5


• Vikings at Packers: GB -3, total 41.5


• Jaguars at Titans: JAX -10.5, total 46.5


• Dolphins at Colts: IND -3.5, total 38.5


• Panthers at Saints: NO -2.5, total 48.5


• Bills at Jets: BUF -8.5, total 50.5


• Seahawks at Raiders: SEA -6.5, total 40.5


• Rams at Cardinals: LAR -9.5, total 39.5


• 49ers at Cowboys: SF -3.5, total 55.5


• Steelers at Bengals: CIN -3.5, total 49.5


• Chargers at Ravens (Monday): BAL -4.5, total 38.5

Games to watch closely:

• 49ers-Cowboys: The best scoring environment on the board.


• Patriots-Lions: Strong quarterback and receiver potential.


• Bills-Jets: Allen's legs are a big factor.


• Chiefs-Falcons: Mahomes has real fantasy upside.


• Chargers-Ravens: The lowest total of the week makes it a tough passing environment.

Our calls on every game, moneyline, spread and total, are on NFL picks.

Injury and Starting-Quarterback Watch

From our NFL injury report as of Friday morning. Verify each one before kickoff.

• Kyler Murray, Vikings: Doubtful (hamstring). Minnesota's starter isn't settled.


• Carson Wentz, Vikings: Questionable.


• Kirk Cousins, Vikings: New to Minnesota. Watch for the starting decision.


• Gardner Minshew, Cardinals: Injured reserve, expected to miss the season.


• Carson Beck, Cardinals: Expected to start.


• Sam Darnold, Seahawks: Out until late November.


• Drew Lock, Seahawks: Questionable.


• Deshaun Watson, Browns: Expected back as the starter.


• Lamar Jackson, Ravens: Injured reserve until mid-December.


• Malik Willis, Dolphins: Injured reserve. Confirm Miami's starter before you play anyone from that game.


• Patrick Mahomes, Jared Goff and Justin Herbert: Not on the injury report as of Friday.

Inactive lists and official team announcements override everything above.

FantasyDailies Final QB Rankings

1. Josh Allen


2. Patrick Mahomes


3. Joe Burrow


4. Brock Purdy


5. Drake Maye


6. Jared Goff


7. Dak Prescott


8. Matthew Stafford


9. Trevor Lawrence


10. Michael Penix Jr.

• Best DFS value: Drake Maye.


• Best high-ceiling stack: Brock Purdy and the 49ers passing game.


• Best rushing quarterback prop: Josh Allen.


• Most interesting new quarterback: Kirk Cousins, if Minnesota hands him the job.


• Biggest rookie gamble: Carson Beck.


• Quarterback to avoid building around: Drew Lock.

Quarterback matters more than usual this weekend. Don't chase a cheap price just because a backup is suddenly starting. New systems, short preparation, line injuries and tough defenses can turn a bargain into a DFS disaster. Check the final injury reports, confirm the starters, compare the numbers and don't pay a premium for a quarterback who hasn't earned it. Not sure who to start? The AI lineup analyzer grades every start and sit.

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