NFL Week 10 Late Slate and Sunday Night Football: Lines, Injuries, DFS, Props, Teasers and Parlays

NFL Week 10 Sunday Late Games and SNF Preview: Odds, Props, Teasers, Parlays

FantasyDailies.com | Sunday, November 15, 2026 | Week 10 | Your Edge Every Day

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The afternoon slate brings three games with significant fantasy and betting potential before we finish the night with an AFC North showdown between Pittsburgh and Cincinnati.

San Francisco and Dallas could be the offensive fireworks show of the afternoon, while Seattle and the Rams enter as substantial road favorites. Then we get Steelers-Bengals under the Sunday Night Football lights.

Every line below is the current number on our board. Our moneyline, spread and total call on every game is on the NFL picks page, and the NFL parlay generator builds off those same calls, so it never hands you a leg that fights our own pick. Let's break down the board.

Game 1: Seattle Seahawks at Las Vegas Raiders

Seattle Seahawks at Las Vegas Raiders | 4:05 PM ET | CBS

The lines: Moneyline SEA -300 · LV +245 | Spread SEA -6.5 · LV +6.5 | Total 40.5

Seattle enters as a substantial road favorite, but there's a big quarterback change to account for. Sam Darnold has been ruled out with quadriceps and rib injuries, and Drew Lock gets the start. Lock is managing an oblique injury and dealt with an elbow issue earlier in the week. Coach Mike Macdonald said the oblique is something the team can manage with him playing. If it flares up, rookie Jalen Milroe is next.

The Seahawks have a strong defensive matchup against a Las Vegas offense that could struggle to sustain drives. The Raiders need to establish Ashton Jeanty early and keep Seattle's defense from dictating the game. With Lock under center and a 40.5 total, this has the look of a grind.

Injury report:

• Seattle: Sam Darnold OUT (quadriceps, rib). Drew Lock expected to start (oblique).

Final designations and inactives are on our NFL injury report.

DFS and fantasy targets:

• Zach Charbonnet: potential rushing volume.
• Jaxon Smith-Njigba: primary receiving option.
• Rashid Shaheed: big-play tournament upside.
• Ashton Jeanty: volume-based fantasy play.
• Brock Bowers: receiving upside, particularly in PPR.
• Seattle defense: strong tournament consideration.

Player props to investigate: Charbonnet rushing attempts, Jeanty rushing and receiving yards, Smith-Njigba receptions, Bowers receiving yards, Seattle team sacks and Drew Lock passing attempts. Every line is on the NFL props board.

Our call: moneyline, spread and total on the NFL picks page. Watch it first on the SEA at LV simulation, and see weather, injuries and every line on the game page.

Game 2: Los Angeles Rams at Arizona Cardinals

Los Angeles Rams at Arizona Cardinals | 4:05 PM ET | CBS

The lines: Moneyline LAR -520 · ARI +400 | Spread LAR -9.5 · ARI +9.5 | Total 39.5

Los Angeles comes in as the biggest favorite of the late window, but both teams are short-handed.

Arizona turns to rookie Carson Beck, its third starting quarterback in three games. Gardner Minshew and receiver Michael Wilson are both on injured reserve, and Jacoby Brissett was traded to Baltimore this week.

The Rams have their own receiver problems. Puka Nacua is out for an extended stretch with knee and toe injuries, and Davante Adams is on injured reserve with a hamstring, with Week 12 the realistic target for his return. Tight end Terrance Ferguson and guard Steve Avila are ruled out too.

This is a game where the spread and the total deserve separate thought. At 39.5, the market expects the Rams can win comfortably without it turning into a shootout.

Injury report:

• Rams: Puka Nacua OUT (knee, toe; extended absence). Davante Adams on IR (hamstring). Terrance Ferguson OUT (hamstring). Steve Avila OUT. Trent McDuffie questionable (back).
• Cardinals: Carson Beck to start. Gardner Minshew and Michael Wilson on IR.

Final designations and inactives are on our NFL injury report.

DFS and fantasy targets:

• Rams quarterback: consider depending on salary, with the top two receivers out.
• Rams lead running back: potential workload advantage as a big favorite.
• Rams top healthy receiver: inherits targets with Nacua and Adams out.
• Arizona's lead running back: potential volume if the Cardinals keep it close.
• Arizona's primary receiver: garbage-time production potential.

Player props to investigate: Rams quarterback passing touchdowns, Rams running back rushing yards, Carson Beck passing attempts, Rams receiving yards and anytime touchdown scorers. Every line is on the NFL props board.

Our call: moneyline, spread and total on the NFL picks page. Watch it first on the LAR at ARI simulation, and see weather, injuries and every line on the game page.

Game 3: San Francisco 49ers at Dallas Cowboys

San Francisco 49ers at Dallas Cowboys | 4:25 PM ET | FOX

The lines: Moneyline SF -210 · DAL +176 | Spread SF -4.5 · DAL +4.5 | Total 55.5

This is the most attractive fantasy matchup of the entire week. The 55.5 total is the highest on the board, five points clear of any other Sunday game.

San Francisco's attack revolves around getting Christian McCaffrey involved in multiple ways. If Dallas can't contain him in the passing game, it could become a long afternoon for the Cowboys. Receiver Mike Evans isn't trending toward a return this week.

Dak Prescott and the Dallas passing game have the firepower to keep this close, but the Cowboys are banged up at tight end and in the secondary. Jake Ferguson is expected to miss multiple weeks, which opens targets for everybody else.

Injury report:

• 49ers: Mike Evans not trending toward a Week 10 return.
• Cowboys: P.J. Locke OUT. Jake Ferguson and Tyler Goodson expected to miss multiple weeks. George Pickens, Jonathan Mingo and Donovan Ezeiruaku had uncertain status this week; check the final designations.

Final designations and inactives are on our NFL injury report.

DFS and fantasy targets:

• Christian McCaffrey: elite dual-threat potential.
• Dak Prescott: strong tournament quarterback option.
• CeeDee Lamb: high-upside receiving option, especially with Ferguson out.
• George Pickens: salary and availability consideration; confirm he's active.
• George Kittle: receiving and touchdown potential.
• Brock Purdy: attractive in the highest-total game of the week.
• Javonte Williams: rushing workload in the Dallas committee.
• Deebo Samuel: receiving and rushing versatility.

Player props to investigate: McCaffrey rushing and receiving yards, Lamb receptions, Prescott passing yards, Kittle receiving yards, Pickens receiving yards if active, and both quarterbacks' passing touchdowns. Every line is on the NFL props board.

Our call: moneyline, spread and total on the NFL picks page. Watch it first on the SF at DAL simulation, and see weather, injuries and every line on the game page.

Game 4: Pittsburgh Steelers at Cincinnati Bengals

Pittsburgh Steelers at Cincinnati Bengals | 8:20 PM ET | NBC | Sunday Night Football

The lines: Moneyline PIT +150 · CIN -178 | Spread CIN -3.5 · PIT +3.5 | Total 49.5

Sunday Night Football brings an AFC North showdown with both teams in the thick of the division race.

Cincinnati enters as the home favorite, and the 3.5-point spread sits right on top of the key number of 3. The Bengals have the weapons to put points on the board. Pittsburgh needs to create pressure, control the running game and finish in the red zone.

Cincinnati's secondary is thin: safety Kyle Dugger is out and cornerback Jalen Davis is doubtful. That's worth knowing before you take a Pittsburgh receiver like DK Metcalf.

Injury report:

• Bengals: Kyle Dugger OUT (quad). Jalen Davis (hamstring), Andrei Iosivas (thumb) and Brian Parker II (knee) DOUBTFUL.
• Steelers: Derrick Harmon QUESTIONABLE (foot), designated to return from IR and a full participant Friday.

Final designations and inactives are on our NFL injury report.

DFS and fantasy targets:

• Joe Burrow: strong quarterback consideration.
• Ja'Marr Chase: premium receiving option.
• Tee Higgins: receiving and touchdown upside.
• Bengals running back: workload and red-zone consideration.
• DK Metcalf: big-play receiving upside against a depleted secondary.
• Steelers lead running back: potential volume play.
• Steelers tight end: salary-dependent PPR option.

Player props to investigate: Burrow passing yards, Chase receiving yards, Higgins receptions, Pittsburgh quarterback passing attempts, Metcalf receiving yards, running back rushing attempts and anytime touchdown scorers. Every line is on the NFL props board.

Our call: moneyline, spread and total on the NFL picks page. Watch it first on the PIT at CIN simulation, and see weather, injuries and every line on the game page.

Top DFS Plays: Late Afternoon and Night

Quarterbacks

• Dak Prescott: strong tournament consideration.
• Brock Purdy: the highest-total game of the week.
• Joe Burrow: Sunday night upside.
• Drew Lock: salary-dependent only; the oblique adds risk.

Running backs

• Christian McCaffrey: premium workload and receiving upside.
• Zach Charbonnet: potential value.
• Ashton Jeanty: volume.
• Javonte Williams: salary-dependent option.

Wide receivers

• CeeDee Lamb: high ceiling.
• Ja'Marr Chase: premium option.
• DK Metcalf: big-play potential.
• Jaxon Smith-Njigba: strong receiving consideration.
• Deebo Samuel: versatile weapon.

Tight ends

• George Kittle: strong tournament option.
• Brock Bowers: receiving upside.
• Pittsburgh's starting tight end: potential salary value.

Tournament stacks to consider: Prescott + Lamb, Purdy + Kittle, Burrow + Chase, with a bring-back from the other side in each. Check our NFL projections and build on the NFL DFS lineup tools.

These are player-pool suggestions, not confirmed salary bargains. Verify salary, active status and projected workload before you lock.

The FantasyDailies NFL Teaser and Parlay Center

Teasers should be built around the key NFL scoring margins, 3 and 7. Don't simply take the teams you think will win. Look at the adjusted spread, the final number and the price you're paying. Here's what every late-window number becomes, both sides, so you can pair your legs with our calls on the picks page:

The classic six-point teaser takes a favorite of 7.5 to 8.5, or an underdog of 1.5 to 2.5, through both 3 and 7. Nothing in the late window sits in that range, so read each leg on its own merits. Bengals -3.5 down to +2.5 and Rams -9.5 down to -3.5 are the cleanest moves: the first crosses 3, the second crosses 7. Ten-point teasers give you more room but cost more, so don't assume extra points automatically mean value. Two-team teaser prices vary, so confirm the price and rules before you place it. Build yours on the NFL teaser generator.

Same-game parlay ideas

• 49ers at Cowboys: the highest total of the week, so lean into correlation: a quarterback passing yards over, McCaffrey receiving yards over and a Lamb receptions over all need the same shootout game script.
• Seahawks at Raiders: a Jeanty rushing yards over pairs naturally with a game where Lock is managing an injury and the total sits at 40.5.
• Rams at Cardinals: a Rams running back anytime touchdown fits a big favorite missing its top two receivers.
• Steelers at Bengals: a Burrow passing yards over and a Chase receiving yards over move together.

Same-game prices include correlation adjustments and vary, so check the posted number before you place it.

Multi-game parlay builds

• The favorites build: the late-window moneylines on our side of each game. Seattle at -300 and the Rams at -520 barely move the payout on their own, which is why the spread calls usually do more work.
• The offensive production build: the two biggest totals on the board, 49ers-Cowboys at 55.5 and Steelers-Bengals at 49.5, with one quarterback passing yards over from each.
• The underdog build: the three late dogs getting points, Raiders +6.5, Cowboys +4.5 and Steelers +3.5. High risk, but exposure to three potentially competitive games.

Let the NFL parlay generator fill these in off our calls, then run the slip through the Parlay Doctor before you place it.

Touchdown scorer parlays

• Two-leg: Christian McCaffrey and Ja'Marr Chase anytime touchdown.
• Three-leg: George Kittle, CeeDee Lamb and Tee Higgins anytime touchdown.
• Four-leg long shot: McCaffrey, Chase, DK Metcalf and Kittle anytime touchdown.

Touchdown markets are volatile. Verify availability and the posted prices on the NFL props board.

Monday Night: New Quarterbacks Everywhere

Week 10 is a week of new faces under center. Kirk Cousins, traded to Minnesota from Las Vegas this week, starts for the Vikings at Green Bay in the early window. On Monday night, Jacoby Brissett, acquired from Arizona this week, starts for Baltimore against the Los Angeles Chargers, with Lamar Jackson out with a thumb injury. Our board has Baltimore -4.5 with a 38.5 total. Run it on the Chargers at Ravens simulation.

FantasyDailies Final Word

The late slate offers several different ways to attack the board, but don't confuse a high projected total with guaranteed fantasy production. Watch the final inactives, especially Seattle's quarterback, the Rams' receiving corps and the Dallas-San Francisco skill players.

Build around opportunity, not reputation. Don't force six-leg parlays just because the payout looks attractive.

Watch every game live, play by play, in Game Zone on FantasyDailies TV on Roku, Amazon Fire TV and Apple TV, and take the parlay generator with you in the app for iPhone and Android.

Your Edge Every Day.

Lines are from our board as of Saturday and can move before kickoff. Injury statuses can change before inactives are announced. Please play responsibly; must be 21+.