Week 2 — Lions at Bills opens the second week

Week 2 odds, lines & our picks for every game →

💰 Week 2 odds & betting preview← All 18 weeks · 2026 NFL schedule

What this page is: the complete Week 2 slate — every game and kickoff time in ET, the line when we made our pick and the line now, our pick with its result, the final score and the box score, plus the weather and the injury report for every game.

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💰 Week 2 Odds📊 Player Props🥊 Matchups📅 Full Schedule

Week 2 — all 16 games

Every kickoff in Eastern. Tap a game for its matchup page: the series since 2002, the last ten meetings, rest and travel edges, and where the house board has it.

Thursday, September 17
Lions at Bills8:15 PM ET🎯 See our picks →
Sunday, September 20
Panthers at Falcons1:00 PM ET🎯 See our picks →Vikings at Bears1:00 PM ET🎯 See our picks →Eagles at Titans1:00 PM ET🎯 See our picks →Steelers at Patriots1:00 PM ET🎯 See our picks →Packers at Jets1:00 PM ET🎯 See our picks →Browns at Buccaneers1:00 PM ET🎯 See our picks →Saints at Ravens1:00 PM ET🎯 See our picks →Bengals at Texans1:00 PM ET🎯 See our picks →Jaguars at Broncos4:05 PM ET🎯 See our picks →Raiders at Chargers4:05 PM ET🎯 See our picks →Commanders at Cowboys4:25 PM ET🎯 See our picks →Seahawks at Cardinals4:25 PM ET🎯 See our picks →Dolphins at 49ers4:25 PM ET🎯 See our picks →Colts at Chiefs8:20 PM ET🎯 See our picks →
Monday, September 21
Giants at Rams8:15 PM ET🎯 See our picks →
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